Darren Aronofsky's drama The Wrestler starring Mickey Rourke, which gets its world premiere at Venice later this month, will close the festival.
Organisers have programmed a newly restored print of Max Ophuls' Lola Montes as the spotlight retrospective and as previously announced Laurent Cantet's Palme d'Or winner The Class will open the festival.
French films feature heavily in the line-up, among them Arnaud Desplechin's family drama A Christmas Tale, Agnes Jaoui's Let It Rain and Olivier Assayas' Summer Hours.
From Cannes comes Israeli director Ari Folman's animated wartime autobiography and French co-production Waltz With Bashir, Steven Soderbergh's two-part Che epic starring Benicio Del Toro, Steve McQueen's Hunger, Matteo Garrone's Grand Prize winner Gomorra and Sergey Dvortsevoy's Russian tale Tulpan.
Wong Kar Wai's Ashes Of Time Redux, Mike Leigh's Happy-Go-Lucky and Jia Zhangke's 24 City are also scheduled to screen.