Greg Behrendt and Liz Tuccillo's bestselling novel of the same name serves as the inspiration for the project about cross-gender misunderstandings in love.
Flower Films principals Nancy Juvonen and Drew Barrymore are producing based on an adapted screenplay by Abby Kohn and Marc Silverstein. New Line production executives Michele Weiss and Michael Disco are overseeing for the studio.
Kwapis most recently directed the upcoming comedy License To Wed starring Robin Williams and Mandy Moore that will open through Warner Bros on Jul 4.
His other feature credits include The Sisterhood Of The Traveling Pants and He Said, She Said.
'Ken Kwapis is acutely aware of human nature - equally fascinated by its nuance and absurdity,' Juvonen said.
Behrendt and Liz Tuccillo previously worked together on Sex And The City as a consultant and writer respectively.