Michael London and Janice Williams of Groundswell Productions will produce the feature based on Christina Baker Kline’s bestselling novel.
Christopher Monger, whose credits include Temple Grandin and The Englishman Who Went Up A Hill But Came Down A Mountain, will adapt the screenplay.
Orphan Train was published in 2013 and is inspired by real events, telling the story of two women from different generations who form a bond in Maine when they realise they share a common past.
The orphan trains placed abandoned children from the East Coast in homes with Midwest farmland families and ran from 1854-1929.
Asher Goldstein and Shary Shirazi will oversee the project for Broad Green Pictures.