Curzon Artificial Eye has taken UK rights to Helen Hunt's Then She Found Me, starring Hunt, Colin Firth, Bette Midler and Matthew Broderick.
Then She Found Me is one of five new titles that Curzon Artificial Eye has picked up on the autumn festival circuit.
An adaptation of Elinor Lipman's 1991 novel, Hunt's directorial debut world premiered in Toronto.
Also newly acquired is Venice Special Jury Prize winner and critical favourite La Graine Et Le Mulet by Apdellatif Kechiche.
Meanwhile, the UK buyer has snapped up La Fille Coupee En Deux by veteran French auteur Claude Chabrol, which screened in Venice out of competition.
Curzon Artificial Eye has also picked up Berlin, Julian Schnabel's documentary about Lou Reed's performance of his 1973 album Berlin for five nights at Saint Ann's Warehouse, Brooklyn, in December 2006.
Having already bought the Cannes competition winner Four Months, Three Weeks & Two Days, the British distributor has acquired another Romanian film, Cristian Nemescu's California Dreamin' (winner of Un Certain Regard.)
Curzon Artificial Eye was formed last year by the merger of veteran UK arthouse distributor Artificial Eye Film Company with Curzon Cinemas (which runs London cinemas the Curzon Mayfair, Curzon Soho, The Chelsea Cinema, The Renoir and the Richmond Filmhouse.)
'These additional acquisitions to an already busy year represent a compelling mix of both established and exciting new directors, and signal both a continuing commitment to the company's tradition and a willingness to expand the scope and breadth of its acquisition and distribution strategy,' said Curzon Artificial Eye's CEO Philip Knatchbull in a statement.