Urban previously appeared in Star Trek, The Lord Of the Rings, The Bourne Supremacy and forthcoming Black Water Transit.
Laurence Malkin directs and producers are Paul Schiff, Tai Duncan and Roseanne Korenberg.
Horse starts shooting in New Mexico this summer. Annie McCarthy is casting.
The story follows an undercover FBI agent and a crime lord whose lives collide over a heroin deal in Albuquerque.
The previously announced cast members are Diego Luna, Luis Guzman, Adriana Barraza, and Benito Martinez. Content has already done more than a dozen territory sales.