Andrew Wagner directed from a screenplay he adapted with Fred Parness from Brian Morton's novel about a former literary giant whose life of solitude is shaken up by a graduate student with a self-serving agenda.
Roadside Attractions plans an autumn release to qualify for awards season contention, and will work with The Little Film Company on the film's international roll-out.
The film had its world premiere in dramatic competition at the Sundance Film Festival in January.
'This is Frank's year in the theatre and people will soon discover that the same is true for film,' Roadside co-presidents Howard Cohen and Eric d'Arbeloff said in a joint statement.
'Andrew Wagner has crafted an extraordinary and moving film about one man's literary life in Manhattan. The role of Leonard Schiller might be a career-best film performance for Frank - one that audiences everywhere will love.'
Langella won the Tony award at the weekend for his role as Richard Nixon in the stage play Frost/Nixon. He will reprise his role this summer in Ron Howard's film version.
Cohen and d'Arbeloff negotiated the deal with Cinetic Media on behalf of the film-makers.