Paramount’s super autumn continued as it launched DreamWorks Animation’s Megamind at the top on an estimated $47.7m.

Overall weekend box office for the top 12 releases came in at $146m, the highest weekend since the July 23-25 period when Inception ruled the waves.

Megamind is well positioned to consolidate in the weeks ahead. It is voiced by Will Ferrell, Brad Pitt and Tina Fey and follows a villain’s change of heart after he unexpectedly wipes out his heroic nemesis.

Warner Bros’ comedy Due Date from The Hangover’s Todd Phillips opened in second place on $33.5m and pits Robert Downey Jr against Zach Galifianakis on an event-filled road trip.

Lionsgate’s awards season hopeful For Colored Girls launched in third on $20.1m. The ensemble drama stars Kimberly Elise, Thandie Newton and Anika Noni Rose.

Lionsgate’s Saw 3D tumbled 64% and four places to number five in its second weekend, adding $8.2m for $38.8m. Paramount’s Jackass 3-D ranks seventh on $110.8m after four weekends.

There were two notable limited launches. Summit opened Doug Liman’s thriller Fair Game in 15th place on $700,000 from 46 for a $15,217 average while Fox Searchlight debuted Danny Boyle’s awards season contender 127 Hours in four theatres for $266,000 and a stunning $66,500 average.

Next weekend’s wide releases include Fox’s action thriller Unstoppable starring Denzel Washington and Chris Pine; Universal’s alien abduction thriller Skyline; and Paramount’s comedy MorningGlory with Harrison Ford, Rachel McAdams and Diane Keaton.

Estimated Top 10 North America Nov 5-7, 2010

Film (Dist) / Est wkd gross / Est total to date

1 (-) Megamind (Paramount-DreamWorks Animation) PPI $47.7m –

2 (-) Due Date (Warner Bros) WBPI $33.5m –

3 (-) For Colored Girls (Lionsgate) $20.1m –

4 (3) Red (Summit) Summit Int’l $8.9m $71.9m

5 (1) Saw 3D (Lionsgate) Lionsgate $8.2m $38.8m

6 (2) Paranormal Activity 2 (Paramount) PPI $7.3m $77.2m

7 (4) Jackass 3-D (Paramount) PPI $5.1m $110.8m

8 (5) Hereafter (Warner Bros) WBPI $4m $28.7m

9 (6) Secretariat (Buena Vista) WDSMPI $4m $50.9m

10 (7) The Social Network (Sony) SPRI $3.6m $85m