The military epic has amassed $32m from foreign revenues in less than three weekends and should prove too strong for its rivals yet again.
Zack Snyder's take on the ancient Battle of Thermopylae has already won the hearts and minds of domestic audiences and launches in France on Mar 21, followed by the UK, Spain and Italy and Mexico on Mar 23.
300 also opens in Belgium and French-speaking Switzerland on Mar 21, Holland on Mar 22, and Norway on Mar 23.
Meanwhile, WBPI figures put The Departed on $155.5m including non-WBPI territories, Happy Feet on $175m including Roadshow territories, Blood Diamond on $101.9m, Letters From Iwo Jima on $53.4m, and Music And Lyrics on $57.2m including Roadshow territories.
Paramount/PPI's Eddie Murphy comedy Norbit, currently on $34.6m, looks good to finish the weekend in second place with eight launches including Italy on Mar 23.
Elsewhere, the Mark Wahlberg thriller Shooter opens day-and-date with North America in Brazil on Mar 23, while drama Freedom Writers opens in two territories including Australia on Mar 22, and has amassed $2.5m to date.
Universal/UPI's crime caper Smokin' Aces ventures into South Africa on Mar 21 and stands at $17.7m, while comedy The Break Up goes out in South Korea on Mar 22. Apartheid drama Catch A Fire opens in the UK on Mar 23, while romantic comedy The Holiday, which stands at $129.4m, arrives in Japan on Mar 24.
Sony Pictures Releasing International (SPRI) opens The Pursuit of Happyness in Russia and Hong Kong on Mar 22, when executives will look to both openings to push the drama's overseas tally towards $150m. As of Mar 19 it stood at $135.5m.
The 9/11-related drama Reign Over Me opens in Australia on Mar 22, day-and-date with its North American launch, while romantic comedy Catch And Release goes out in the UK on Mar 23.
Latest figures as of Mar 19 put Ghost Rider on $86.2m through all distributors, Marie Antoinette on $43.9m, Stranger Than Fiction on $11.3m, and Casino Royale on $426.5m.
It looks like being a relatively quiet weekend for Buena Vista International. The distributor opens the thriller Deja Vu, currently on $107.8m, in China on Mar 23. Comedy Wild Hogs has grossed $8m from the early stages of its run.
Fox International has a scattered slate this weekend. The comedy spoof Epic Movie launches in Brazil on Mar 23 and has taken $25.6m to date, while Borat arrives in two territories including Taiwan on Mar 24 and stands at $130.7m.
The Last King Of Scotland opens in Russia on Mar 22 and Fox International chiefs will look to boost the drama's $24.2m tally. The distributor holds rights to the psychological thriller Premonition in one territory, Taiwan, and launches it there on Mar 24.
Latest figures put Rocky Balboa on $77.1m through all distributors, while Notes On A Scandal has taken $23.5m, Little Miss Sunshine stands at $37.6m, Pathfinder has grossed $7.9m, and Apocalypto stands at $61.9m through all distributors.