Joel and Ethan Coen's Burn After Reading will open the 65th edition of the Venice Film Festival as a world premiere.
The film's classification as a gala or competition screening will be announced at a later date, the Biennale has said.
In either case, the follow-up to the Coen Brother's celebrated No Country For Old Men assures a glamorous opening night for the festival, which will also mark artistic director Marco Mueller's renewed mandate and his fifth year on the Lido.
Burn After Reading, a dark spy comedy, stars John Malkovich as an ousted CIA official whose unpublished memoirs fall accidentally into the clutches of two employees at a gym. The film also stars Venice regular George Clooney, Frances McDormand, Tilda Swinton, Richard Jenkins and Brad Pitt.
The film is a Working Title Production, produced by Joel and Ethan Coen, with Tim Bevan, Eric Fellner and Robert Graf executive producing. It will go out via Universal in the UK on Sept 5. Focus Features will handle the Sept 12 US rollout and Medusa will distribute the film in Italy.
This year's Venice Film Festival runs Aug 27-Sept 6.