The selections represent seven world premieres, six European premieres and six UK premieres.
The Film4 FrightFest opens with Jonathan King's hit New Zealand zombie sheep film Black Sheep. That screening is followed by Australian crocodile thriller Black Water.
Other features include Shrooms, Joshua, The Orphanage, All The Boys Love Mandy Lane, Disturbia, Day Watch, The Signal, Waz, The Girl Next Door, P2, Seed, Postal, Spiral and Botched.
Special events during the festival will include director Adam Green giving a live commentary for Hatchet, producer Andrew Macdonald presenting deleted scenes from 28 Weeks Later, and director Paul Andrew Williams and actress Reece Shearsmith presenting a preview of The Cottage.
Directors set to attend include Juan Antonio Bayona for The Orphanage; Tom Shankland for WAZ; Uwe Boll for Seed and Postal; Kit Ryan for Botched and Jonathan King for Black Sheep.
Festival director Alan Jones said: 'FrightFest has always been about being informative, recognizing genre directions and providing a one- stop event to celebrate all that's innovative and important in the global cinefantastique field. Thanks to Film4's sponsorship we have been able to achieve our goal to provide the best all-round viewing experience with the widest reach in our ever-expanding eight-year history.'