The Sutherland is for the most original and imaginative first feature at the festival.
The Sutherland jury said the film was 'an astonishing and courageous film which captures a universal story with real style.'
Joanna Hogg's Unrelated won the Fipresci international critics' award. The UK production is about a middle-aged woman who goes on an Italian holiday with her extended family.
Sarah Gavron, director of Brick Lane, won the Alfred Dunhill UK Film Talent Award, which comes with $30,000 (£15,000).
The Times BFI LFF Grierson Award for best feature documentary went to The Mosquito Problem And Other Stories by Andrey Paounov.
Finally, the 12th annual Satyajit Ray Award went to Cristian Nemescu for California' Dreamin.
The TCM Short Film Award went to Tom Tagholm for A Bout De Truffe.
The LFF closed with a gala screening of Wes Anderson's The Darjeeling Limited.
The festival screened 185 feature films. There was record audience attendance and more than 1000 industry professionals, including a record 191 buyers and sellers.
Festival artistic director Sandra Hebron said: 'It has been extremely heartening to see such an enthusiastic response to the Festival from the public, the media and the industry at large.'
Guests included David Lynch, Carlos Reygadas, Julian Schnabel, Francois Ozon, David Sington, Nicolas Philibert, Asif Kapadia, Amitabh Bachchan, David Cronenberg, Christine Vachon, Jason Reitman, Ang Lee, Halle Berry, Naomi Watts, Adrien Brody, and many other film-makers and actors.