Amy Adams stars as a fairy tale princess who is thrust into that also stars Patrick Dempsey, James Marsden and Susan Sarandon.
This was the second best Thanksgiving weekend launch in history behind Toy Story 2's $80.1m five-day haul.
Opening in second place was Screen Gems' comedy-drama This Christmas starring Delroy Lindo and Loretta Devine on $18.6m over three and $27.1m over five.
Beowulf fell two places to third and added $16.2m for $56.4m after two weekends, while Fox's action thriller Hitman starring Timothy Olyphant opened in fourth place on $13m over three and $21m over five days.
The only other new released to break into the top 10 was MGM/Dimension's horror tale The Mist with Thomas Jane, which opened in ninth place on $9.2m over three days and $115.8m over five.
The Weinstein Company's Bob Dylan homage I'm Not There starring Cate Blanchett, Heath Ledger and Ben Whishaw, among others, opened on 30 screens and grossed $1m over the five-day period for an average of $5,823.
The result gave director Todd Haynes his biggest launch and the film scored a record debut at New York City's Film Forum on $45,000 over five days.
Next weekend's only wide release is MGM/TWC's thriller Awake starring Jessica Alba and Hayden Christensen.
Estimated Top 10 North America Nov 23-25, 2007
Film (Dist)/Int'l dist/Est wkd gross/Est total to date
1 (-) Enchanted (Buena Vista) WDSMPI $35.3m $50m
2 (-) This Christmas (Screen Gems) SPRI $18.6m $27.1m
3 (1) Beowulf (Paramount) WBPI $16.2m $56.4m
4 (-) Hitman (Fox) Fox Int'l $13m $21m
5 (2) Bee Movie (DreamWorks-Paramount) PPI $12m $112.1m
6 (4) Fred Claus (Warner Bros) WBPI $10.7m $53.1m
7 (-) August Rush (Warner Bros) WBPI $9.4m $13.3m
8 (3) American Gangster (Universal) UPI $9.2m $115.8m
9 (-) The Mist (MGM/Dimension) TWC $9.1m $13m
10 (7) No Country For Old Men (Miramax) Paramount Vantage Int'l $8.1m $16.6m