Fox plans a December holiday release in Central and South American territories following the Nov 16 US release through New Line.
Twentieth Century Fox director of acquisitions Ray Strache brought the film into the Fox fold.
Fox business affairs executive Megan O'Brien negotiated the deal with partner/head of business affairs Andrew Molasky on behalf of Stone Village. Summit International is handling overseas sales.
Mike Newell directed the sprawling Latin American saga of unrequited love that stars stars Javier Bardem, Catalina Sandino Moreno, Live Schreiber, Fernanda Montenegro and John Leguizamo.
Ronald Harwood adapted the screenplay and Stone Village partner Scott Steindorff produced.
'We at Fox in Latin America are thrilled with this amazing and spectacular film that brings justice to the brilliant, romantic novel from Gabriel Garcia Marquez,' Fox Latin America's executive vice president Eduardo Echeverria said.
'Moviegoers all over the region and beyond will be blown away by Mike Newell's masterpiece. We will not leave any stone unturned to ensure that Love In The Time Of Cholera receives the largest audience ever for a Latin novel turned into a film.'
'We can't imagine a better homecoming for Love In The Time Of Cholera than through Fox Latin America,' Steindorff said.
'No one is better prepared than Fox to shepherd Cholera home to the countries responsible for the book and Garcia Marquez' global success.'