Walt Disney Studios Motion Pictures International's (WDSMPI) animated hit is now the second biggest international Pixar release behind Finding Nemo's $524.9m. Ratatouille has grossed $577m worldwide.
In Germany, Ratatouille added $3.7m to rank second on $40m after five weekends and is now the biggest animated release of the year.
In third weekends the film added $3.6m for $20m in Italy and $885,000 for $5.6m in Sweden to rank number one for the third consecutive weekend in both territories.
It ranks number one for the fourth weekend in a row in the UK after adding $2.9m for $41.2m, and held on to the top spot for the fifth consecutive weekend in Switzerland where it has amassed $7.3m.
WDSMPI's family release The Game Plan added $2.4m from 650 sites in four countries for $8m, fire by three number one debuts.
It opened in Australia on $1.1m, Singapore on $165,000, and New Zealand on $145,000. The film opens in Taiwan, Hong Kong and Thailand next weekend.
Resident Evil: Extinction made a splash this weekend as it grossed $10.7m through all distributors and $9.9m through Sony Pictures Releasing International (SPRI) on 1,685 screens in 32 markets for $70.9m overall.
Japan provided the most memorable debut of the weekend with $5.1m from 330 screens for second place. Spain generated a $3.4m second place launch from 351 screens, and Chile produced $140,000 from 24 for first place.
The UK and Australia have delivered $5.2m and $2.5m respectively after four weekends, while Brazil has produced $3.8m after five, and Mexico is on $7.3m after seven.
SPRI's comedy Superbad added $3.4m from 1,485 in 39 for $40.3m, fuelled by a fifth place debut in France that produced $1.5m from 350 screens.
The animated release Surf's Up added $5.9m from 1,980 screens in 32 for a solid $72.5m, while the vampire thriller 30 Days Of Night launched in Malaysia and the Philippines on a combined $510,000 from 73 screens.
Mandate International's Saw IV brought in a further $8.2m from 22 territories this weekend, raising the early international running total to $22m.
The horror film opened top in Argentina on $304,000, and added $1.3m from the second weekend in Spain for $5.2m, and $805,000 from the second weekend in Brazil for $2.2m.
DreamWorks-Paramount's comedy remake The Heartbreak Kid raised its running total by $7.5m through PPI from 1,591 venues in 20 territories for $30.3m.
The film opened in nine territories, including a $3.7m haul in Germany from 491 screens, and $1.3m in Mexico from 282 sites.
Fantasy adventure Stardust added $7.3m from 2,436 sites for $73.2m. The largest contribution came from the UK, where $2.7m from 435 screens raised the tally there to $19.3m.
Bee Movie opened strongly in both Russia and Ukraine, taking $2.7m from 429 locations and opening at number one on $542,000 from 63 screens, respectively.
Fox International's family adventure The Seeker: The Dark Is Rising grossed $2.7m from 2,400 screens in 38 markets for $14.8m. The film launched in France on $1.1m on 350 screens.
Die Hard 4.0 added $1.2m from 411 screens in the second weekend in Italy, raising the cumulative total there to $4.2m and the overall international tally to $243m.
Universal/UPI opened the crime saga American Gangster in four Eastern European territories and reported $150,000 from 23 sites. The film will roll out across the rest of the world over the next three months starting in the next two weeks in the UK, France, and Germany.
Action thriller The Kingdom added $5.5m from 1,696 venues in 32 territories for $26m, fired up by nine launches including a number one French debut on $2.1m from 293.
Thriller The Bourne Ultimatum continues to inch toward $200m and raised its tally by $5.3m from 931 venues in 30 to $191.1m. The result was powered by an impressive $4.4m Italian launch in 266 sites.
There are four more territories to open including Japan on November 10 and China on November 15.
Elizabeth: The Golden Age added $4.8m from 800 sites in six territories for an early international total of $8.1m. The historical drama opened in the UK on $2.9m (£1.4m) from 451 venues, and held well in Italy in third place on $1.3m from 258 sites for $4.4m.
Comedy Knocked Up grossed $1.8m from 690 venues in 25 territories for $68.6m. The Spanish debut produced $1.2m from 250 dates.
I Now Pronounce You Chuck And Larry added $1.4m from 788 in 28 to raise the comedy's running total to $62.5m, and the drama Atonement added $530,000 from 160 in six for $25m.
Universal's Brazilian co-production Tropa De Elite ranks third in Brazil after five weekends and added $970,000 from 208 venues for $9.2m.
Warner Bros Pictures International (WBPI) did not report on Sunday and will issue figures on Monday [Nov 5].