The siblings behind global smash Captain America: The Winter Soldier are in talks to direct the two-part Avengers: Infinity War, according to reports circling Hollywood on Monday night.
If confirmed, the development would mean Joe and Anthony Russo are effectively taking over the reins at the Avengers franchise from Joss Whedon.
A spokesperson for Marvel Studios did not confirm the rumours, however it is understood the brothers are lining up to commence production on one overarching Infinity War shoot in 2016.
The first part is due to open on May 4 2018 with the second following one year later.
The Russos are set to begin principal photography in April on Captain America: Civil War, scheduled to open on May 6 2016.
That film follows the events of May 1 opener Avengers: Age Of Ultron after new legislation outlawing superheroes creates two opposing factions led by Iron Man and Captain America.
The Infinity War reports indicate an avalanche of work on the horizon for the siblings, who recently signed a three-year deal with Sony.