Cotillard plays French chanteuse Edith Piaf in Olivier Dahan's La Vie en Rose, which was released theatrically in the US by Picturehouse on June 8.
She previously won the Cesar for best supporting actress for her role in Jean-Pierre Jeunet's A Very Long Engagement and got Cesar nominations for Taxi and Les Jolies Choses.
Her US films include Tim Burton's Big Fish, Ridley Scott's A Good Year and Abel Ferrara's Mary. She will next be seen in L'Ennemi public n° 1, from director Jean-François Richet.
The 2007 Hollywood Film Festival, presented by Starz, will run from October 16 to 22. Previous recipients of the festival's Hollywood Breakthrough Awards include Jamie Foxx, Jake Gyllenhaal, Scarlett Johansson, Keira Knightley and Naomi Watts.